# GO	NS	enrichment	name	ratio_in_study	ratio_in_pop	p_uncorrected	depth	study_count	p_fdr_bh	study_items
hsa05014	XX	e	Amyotrophic lateral sclerosis	47/178	364/8061	4.706637489536348e-24	n.a	47	1.5531903715469948e-21	ACTB, ALS2, ANG, ANXA11, ATXN2, BAX, BCL2L1, C9orf72, CASP1, CAT, CHCHD10, CHMP2B, DCTN1, ERBB4, ERN1, FIG4, FUS, GLE1, GPX1, HNRNPA1, HNRNPA2B1, HSPA5, KIF5A, MAP3K5, MATR3, NEFH, OPTN, PFN1, PRKN, PRPH, SETX, SIGMAR1, SLC1A2, SOD1, SPG11, SQSTM1, TARDBP, TBK1, TNF, TP53, TUBA1A, TUBA4A, TUBB4B, UBQLN2, UBQLN4, VAPB, VCP
hsa05022	XX	e	Pathways of neurodegeneration - multiple diseases	43/178	475/8061	5.167986172857463e-16	n.a	43	8.527177185214811e-14	ALS2, APP, ATXN2, BAX, BCL2L1, C9orf72, CAT, CHMP2B, DCTN1, ERN1, FIG4, FUS, GPX1, GRIA3, HSPA5, HTT, IL1B, IL6, KIF5A, MAP3K5, MAPT, NEFH, NOX4, OPTN, PARK7, PRKN, PRPH, PSEN1, PTGS2, SIGMAR1, SNCA, SOD1, SPG11, SQSTM1, TARDBP, TBK1, TNF, TUBA1A, TUBA4A, TUBB4B, VAPB, VCP, WNT7A
hsa05418	XX	e	Fluid shear stress and atherosclerosis	21/178	139/8061	2.178025152814393e-12	n.a	21	2.3958276680958325e-10	ACTB, CCL2, FOS, GSTA4, GSTM1, GSTM3, GSTP1, HMOX1, IFNG, IL1B, MAP3K5, MMP2, MMP9, NFE2L2, NOS3, PDGFA, PLAT, SQSTM1, TNF, TP53, VEGFA
hsa04657	XX	e	IL-17 signaling pathway	13/178	94/8061	1.2138482786572096e-07	n.a	13	1.0014248298921975e-05	CCL2, CSF3, CXCL10, FOS, IFNG, IL1B, IL6, JUND, LCN2, MMP9, PTGS2, TBK1, TNF
hsa04217	XX	e	Necroptosis	16/178	159/8061	3.803088213536552e-07	n.a	16	2.510038220934124e-05	AIFM1, BAX, CASP1, CHMP2B, HMGB1, IFNA2, IFNG, IL1B, JAK3, PLA2G4A, PYGL, RIPK3, SQSTM1, TNF, TRPM7, XIAP
hsa04210	XX	e	Apoptosis	13/178	136/8061	8.695262885542388e-06	n.a	13	0.0004782394587048	ACTB, AIFM1, BAX, BCL2L1, CTSD, ERN1, FOS, MAP3K5, TNF, TP53, TUBA1A, TUBA4A, XIAP
hsa04933	XX	e	AGE-RAGE signaling pathway in diabetic complications	11/178	100/8061	1.14961157513497e-05	n.a	11	0.0005419597425636	AGT, BAX, CCL2, IL1B, IL6, MMP2, NOS3, NOX4, PRKCD, TNF, VEGFA
hsa05200	XX	e	Pathways in cancer	28/178	531/8061	1.7691934525239946e-05	n.a	28	0.0007297922991661	AGT, BAX, BCL2L1, CREBBP, FGF6, FOS, GSTA4, GSTM1, GSTM3, GSTP1, HMOX1, IFNA2, IFNG, IGF1, IL6, JAK3, MMP2, MMP9, NFE2L2, NOTCH1, PDGFA, PPARG, PTGS2, RXRA, TP53, VEGFA, WNT7A, XIAP
hsa04211	XX	e	Longevity regulating pathway	10/178	89/8061	2.408359537326723e-05	n.a	10	0.0008830651636864	ADIPOQ, ATG5, BAX, CAT, IGF1, PPARG, PPARGC1A, SESN2, SOD2, TP53
hsa05132	XX	e	Salmonella infection	17/178	249/8061	3.324357540301891e-05	n.a	17	0.0010970379882996	ACTB, ACTR3, ANXA2, BAX, CASP1, DCTN1, FOS, IL1B, IL6, IRAK1, KIF5A, PFN1, RIPK3, TNF, TUBA1A, TUBA4A, TUBB4B
hsa05135	XX	e	Yersinia infection	12/178	137/8061	4.675697895475814e-05	n.a	12	0.0014027093686427	ACTB, ACTR3, ARHGEF28, CASP1, CCL2, FOS, IL1B, IL6, IRAK1, LAT, TBK1, TNF
hsa05202	XX	e	Transcriptional misregulation in cancer	14/178	192/8061	8.352846897430644e-05	n.a	14	0.0021203380585785	BAX, BCL2L1, EWSR1, FUS, GRIA3, IGF1, IL6, MMP9, PDGFA, PLAT, PPARG, RXRA, TAF15, TP53
hsa05016	XX	e	Huntington disease	18/178	306/8061	0.0001355767959849	n.a	18	0.0031957387625012	BAX, CREBBP, DCTN1, ERN1, GPX1, GRIA3, HTT, KIF5A, MAP3K5, PPARG, PPARGC1A, SLC1A2, SOD1, SOD2, TP53, TUBA1A, TUBA4A, TUBB4B
hsa04668	XX	e	TNF signaling pathway	10/178	112/8061	0.0001730456949647	n.a	10	0.0036113545981869	CCL2, CXCL10, FOS, IL1B, IL6, MAP3K5, MMP9, PTGS2, RIPK3, TNF
hsa04621	XX	e	NOD-like receptor signaling pathway	13/178	181/8061	0.0001750959805181	n.a	13	0.0036113545981869	ATG5, BCL2L1, CASP1, CCL2, IFNA2, IL1B, IL6, PRKCD, RIPK3, TBK1, TNF, TRPM7, XIAP
hsa04216	XX	e	Ferroptosis	6/178	41/8061	0.0002520732148803	n.a	6	0.0048931859359125	ACSL1, ATG5, CP, HMOX1, MAP1LC3B, TP53
hsa05225	XX	e	Hepatocellular carcinoma	12/178	168/8061	0.0003279601025245	n.a	12	0.0060126018796175	ACTB, BAX, BCL2L1, GSTA4, GSTM1, GSTM3, GSTP1, HMOX1, NFE2L2, SHC1, TP53, WNT7A
hsa05012	XX	e	Parkinson disease	15/178	249/8061	0.0003874398690756	n.a	15	0.0063946930250042	BAX, BCL2L1, ERN1, HSPA5, KIF5A, MAP3K5, MAPT, NFE2L2, PARK7, PRKN, SNCA, TP53, TUBA1A, TUBA4A, TUBB4B
hsa05164	XX	e	Influenza A	12/178	172/8061	0.0004068015862155	n.a	12	0.0063946930250042	ACTB, BAX, CASP1, CCL2, CREBBP, CXCL10, IFNA2, IFNG, IL1B, IL6, TBK1, TNF
hsa04623	XX	e	Cytosolic DNA-sensing pathway	7/178	63/8061	0.0004436360300432	n.a	7	0.0063946930250042	CASP1, CXCL10, IFNA2, IL1B, IL6, RIPK3, TBK1
hsa04620	XX	e	Toll-like receptor signaling pathway	9/178	104/8061	0.0004623361286282	n.a	9	0.0063946930250042	CXCL10, FOS, IFNA2, IL1B, IL6, IRAK1, SPP1, TBK1, TNF
hsa05204	XX	e	Chemical carcinogenesis	8/178	83/8061	0.0004643818263161	n.a	8	0.0063946930250042	CYP2C9, CYP2E1, EPHX1, GSTA4, GSTM1, GSTM3, GSTP1, PTGS2
hsa04932	XX	e	Non-alcoholic fatty liver disease	11/178	150/8061	0.0004650685836366	n.a	11	0.0063946930250042	ADIPOQ, BAX, CYP2E1, ERN1, FOS, IL1B, IL6, MAP3K5, PPARA, RXRA, TNF
hsa04066	XX	e	HIF-1 signaling pathway	9/178	109/8061	0.0006529007530253	n.a	9	0.0086182899399347	ALDOB, CREBBP, ENO1, HMOX1, IFNG, IGF1, IL6, NOS3, VEGFA
hsa04137	XX	e	Mitophagy - animal	7/178	68/8061	0.0007086435370396	n.a	7	0.0089943218162721	ATG5, BCL2L1, OPTN, PRKN, SQSTM1, TBK1, TP53
hsa05144	XX	e	Malaria	6/178	50/8061	0.0007559406932843	n.a	6	0.0092392751401415	CCL2, CSF3, IFNG, IL1B, IL6, TNF
hsa00982	XX	e	Drug metabolism - cytochrome P450	7/178	70/8061	0.000844470265758	n.a	7	0.0099526852750053	CYP2C9, CYP2E1, FMO1, GSTA4, GSTM1, GSTM3, GSTP1
hsa05161	XX	e	Hepatitis B	11/178	162/8061	0.0008877428309889	n.a	11	0.0101019011802187	BAX, CREBBP, FOS, IFNA2, IL6, IRAK1, JAK3, MMP9, TBK1, TNF, TP53
hsa05162	XX	e	Measles	10/178	139/8061	0.0009758872940639	n.a	10	0.0107347602347029	BAX, BCL2L1, FOS, IFNA2, IL1B, IL6, IRAK1, JAK3, TBK1, TP53
hsa03320	XX	e	PPAR signaling pathway	7/178	74/8061	0.0011774098016296	n.a	7	0.012533717243154	ACSL1, ADIPOQ, APOA1, ME1, PPARA, PPARG, RXRA
hsa05143	XX	e	African trypanosomiasis	5/178	37/8061	0.001219638140086	n.a	5	0.0125775183196375	APOA1, IFNG, IL1B, IL6, TNF
hsa05130	XX	e	Pathogenic Escherichia coli infection	12/178	197/8061	0.0013529500220539	n.a	12	0.0133797500001811	ACTB, ACTR3, BAX, CASP1, FOS, IL1B, IL6, IRAK1, TNF, TUBA1A, TUBA4A, TUBB4B
hsa00980	XX	e	Metabolism of xenobiotics by cytochrome P450	7/178	76/8061	0.0013785196969883	n.a	7	0.0133797500001811	CYP2C9, CYP2E1, EPHX1, GSTA4, GSTM1, GSTM3, GSTP1
hsa05134	XX	e	Legionellosis	6/178	57/8061	0.0015198473210991	n.a	6	0.0139319337767418	CASP1, HSF1, IL1B, IL6, TNF, VCP
hsa00480	XX	e	Glutathione metabolism	6/178	57/8061	0.0015198473210991	n.a	6	0.0139319337767418	GPX1, GSR, GSTA4, GSTM1, GSTM3, GSTP1
hsa05171	XX	e	Coronavirus disease - COVID-19	13/178	232/8061	0.0018336034871756	n.a	13	0.0163537608315663	CASP1, CCL2, CSF3, CXCL10, FGA, FOS, IFNA2, IL1B, IL6, IRAK1, TBK1, TNF, VWF
hsa05160	XX	e	Hepatitis C	10/178	157/8061	0.0024390787457555	n.a	10	0.0207473726724991	BAX, CXCL10, IFNA2, IFNG, LDLR, PPARA, RXRA, TBK1, TNF, TP53
hsa04659	XX	e	Th17 cell differentiation	8/178	107/8061	0.0024519622249317	n.a	8	0.0207473726724991	AHR, FOS, IFNG, IL1B, IL6, JAK3, LAT, RXRA
hsa04931	XX	e	Insulin resistance	8/178	108/8061	0.0025992882566378	n.a	8	0.0214441281172625	AGT, IL6, NOS3, PPARA, PPARGC1A, PRKCD, PYGL, TNF
hsa04630	XX	e	JAK-STAT signaling pathway	10/178	162/8061	0.0030646081121379	n.a	10	0.0240843023038212	BCL2L1, CNTF, CREBBP, CSF3, GFAP, IFNA2, IFNG, IL6, JAK3, PDGFA
hsa05131	XX	e	Shigellosis	13/178	246/8061	0.0030652748386681	n.a	13	0.0240843023038212	ACTB, ACTR3, ATG5, BAX, BCL2L1, CASP1, IL1B, PFN1, PRKCD, SQSTM1, TBK1, TNF, TP53
hsa04140	XX	e	Autophagy - animal	9/178	137/8061	0.003240863158621	n.a	9	0.0248717405196501	ATG5, BCL2L1, C9orf72, CTSD, ERN1, HMGB1, PRKCD, SQSTM1, TBK1
hsa04920	XX	e	Adipocytokine signaling pathway	6/178	69/8061	0.0040391714532544	n.a	6	0.0302937858994084	ACSL1, ADIPOQ, PPARA, PPARGC1A, RXRA, TNF
hsa05323	XX	e	Rheumatoid arthritis	7/178	93/8061	0.0043686971801794	n.a	7	0.0320371126546492	CCL2, FOS, IFNG, IL1B, IL6, TNF, VEGFA
hsa04141	XX	e	Protein processing in endoplasmic reticulum	10/178	171/8061	0.0045087568245793	n.a	10	0.0323454293937215	BAX, CANX, ERN1, HSPA5, MAP3K5, NFE2L2, PRKN, UBQLN2, UBQLN4, VCP
hsa04979	XX	e	Cholesterol metabolism	5/178	50/8061	0.0047072107801112	n.a	5	0.0330506288816318	APOA1, APOE, APOH, LDLR, VAPB
hsa05010	XX	e	Alzheimer disease	17/178	369/8061	0.005289612455827	n.a	17	0.0363660856338106	APOE, APP, ERN1, IL1B, IL6, KIF5A, MAP3K5, MAPT, NOX4, PSEN1, PTGS2, SNCA, TNF, TUBA1A, TUBA4A, TUBB4B, WNT7A
hsa05215	XX	e	Prostate cancer	7/178	97/8061	0.0055047855501241	n.a	7	0.0370730455416526	CREBBP, GSTP1, IGF1, MMP9, PDGFA, PLAT, TP53
hsa04918	XX	e	Thyroid hormone synthesis	6/178	75/8061	0.0060877231390268	n.a	6	0.0393911497231147	ALB, CANX, GPX1, GSR, HSPA5, TTR
hsa05214	XX	e	Glioma	6/178	75/8061	0.0060877231390268	n.a	6	0.0393911497231147	BAX, CAMK1G, IGF1, PDGFA, SHC1, TP53
hsa05133	XX	e	Pertussis	6/178	76/8061	0.0064913691484859	n.a	6	0.0411952272884688	CASP1, FOS, IL1B, IL6, IRAK1, TNF
hsa04010	XX	e	MAPK signaling pathway	14/178	294/8061	0.0066994190120946	n.a	14	0.0417133636602121	ERBB4, FGF6, FOS, IGF1, IL1B, IRAK1, JUND, MAP3K5, MAPT, PDGFA, PLA2G4A, TNF, TP53, VEGFA
hsa05140	XX	e	Leishmaniasis	6/178	77/8061	0.0069141339389802	n.a	6	0.041729527509083	FOS, IFNG, IL1B, IRAK1, PTGS2, TNF
hsa04380	XX	e	Osteoclast differentiation	8/178	127/8061	0.0069549212515138	n.a	8	0.041729527509083	FOS, IFNG, IL1B, JUND, PPARG, SQSTM1, TNF, TREM2
hsa05142	XX	e	Chagas disease	7/178	102/8061	0.007220670506737	n.a	7	0.0425503797718435	CCL2, FOS, IFNG, IL1B, IL6, IRAK1, TNF
hsa04064	XX	e	NF-kappa B signaling pathway	7/178	104/8061	0.0080077492999641	n.a	7	0.0463606538418976	BCL2L1, IL1B, IRAK1, LAT, PTGS2, TNF, XIAP
hsa00983	XX	e	Drug metabolism - other enzymes	6/178	80/8061	0.0083021260850472	n.a	6	0.0472362346218207	CYP2E1, GSTA4, GSTM1, GSTM3, GSTP1, NME2
hsa05216	XX	e	Thyroid cancer	4/178	37/8061	0.0085990373304315	n.a	4	0.0480963104922445	BAX, PPARG, RXRA, TP53
hsa04146	XX	e	Peroxisome	6/178	82/8061	0.009332137645198	n.a	6	0.051326757048589	ACSL1, CAT, DAO, HACL1, SOD1, SOD2
hsa00590	XX	e	Arachidonic acid metabolism	5/178	61/8061	0.0108872793256432	n.a	5	0.0588983963518407	CYP2C9, CYP2E1, GPX1, PLA2G4A, PTGS2
hsa04213	XX	e	Longevity regulating pathway - multiple species	5/178	62/8061	0.0116360487103155	n.a	5	0.0619338076516793	ATG5, CAT, IGF1, SOD1, SOD2
hsa05219	XX	e	Bladder cancer	4/178	41/8061	0.0123178558782583	n.a	4	0.0645221022194485	MMP2, MMP9, TP53, VEGFA
hsa05332	XX	e	Graft-versus-host disease	4/178	42/8061	0.0133852380546656	n.a	4	0.0690176337193698	IFNG, IL1B, IL6, TNF
hsa05169	XX	e	Epstein-Barr virus infection	10/178	202/8061	0.0138890134244862	n.a	10	0.0705134527704686	BAX, CXCL10, IFNA2, IL6, IRAK1, JAK3, TBK1, TNF, TP53, VIM
hsa04976	XX	e	Bile secretion	6/178	90/8061	0.014372678786534	n.a	6	0.0708969709729229	ABCB1, ABCC2, EPHX1, LDLR, NR1H4, RXRA
hsa04151	XX	e	PI3K-Akt signaling pathway	15/178	354/8061	0.0143942335005631	n.a	15	0.0708969709729229	BCL2L1, CSF3, ERBB4, FGF6, IFNA2, IGF1, IL6, JAK3, NOS3, PDGFA, RXRA, SPP1, TP53, VEGFA, VWF
hsa05205	XX	e	Proteoglycans in cancer	10/178	205/8061	0.0152665490721671	n.a	10	0.074087664614929	ACTB, ERBB4, IGF1, MMP2, MMP9, TIAM1, TNF, TP53, VEGFA, WNT7A
hsa05222	XX	e	Small cell lung cancer	6/178	92/8061	0.0158812777809558	n.a	6	0.0746448767122662	BAX, BCL2L1, PTGS2, RXRA, TP53, XIAP
hsa05224	XX	e	Breast cancer	8/178	147/8061	0.0159764855966431	n.a	8	0.0746448767122662	BAX, FGF6, FOS, IGF1, NOTCH1, SHC1, TP53, WNT7A
hsa04722	XX	e	Neurotrophin signaling pathway	7/178	119/8061	0.0160599583229421	n.a	7	0.0746448767122662	BAX, IRAK1, MAP3K5, PRKCD, PSEN1, SHC1, TP53
hsa05152	XX	e	Tuberculosis	9/178	180/8061	0.0180858925903485	n.a	9	0.0828936743724308	BAX, CREBBP, CTSD, IFNA2, IFNG, IL1B, IL6, IRAK1, TNF
hsa04622	XX	e	RIG-I-like receptor signaling pathway	5/178	70/8061	0.0189164520427952	n.a	5	0.085512728412636	ATG5, CXCL10, IFNA2, TBK1, TNF
hsa05020	XX	e	Prion disease	12/178	273/8061	0.0196479648326473	n.a	12	0.0876193026320759	BAX, HSPA5, IL1B, IL6, KIF5A, NOTCH1, PRKCD, SOD1, TNF, TUBA1A, TUBA4A, TUBB4B
hsa05218	XX	e	Melanoma	5/178	72/8061	0.0211171025946119	n.a	5	0.0916926823187097	BAX, FGF6, IGF1, PDGFA, TP53
hsa05223	XX	e	Non-small cell lung cancer	5/178	72/8061	0.0211171025946119	n.a	5	0.0916926823187097	BAX, JAK3, KIF5A, RXRA, TP53
hsa04115	XX	e	p53 signaling pathway	5/178	73/8061	0.0222774940152363	n.a	5	0.0942509362183076	BAX, BCL2L1, IGF1, SESN2, TP53
hsa00330	XX	e	Arginine and proline metabolism	4/178	50/8061	0.0240538218128239	n.a	4	0.1004779898510368	ARG1, CKB, DAO, NOS3
hsa00591	XX	e	Linoleic acid metabolism	3/178	29/8061	0.0253903617481997	n.a	3	0.1045593969976125	CYP2C9, CYP2E1, PLA2G4A
hsa04913	XX	e	Ovarian steroidogenesis	4/178	51/8061	0.0256645792630503	n.a	4	0.1045593969976125	IGF1, LDLR, PLA2G4A, PTGS2
hsa04625	XX	e	C-type lectin receptor signaling pathway	6/178	104/8061	0.027274908479676	n.a	6	0.1097648755889401	CASP1, IL1B, IL6, PRKCD, PTGS2, TNF
hsa00030	XX	e	Pentose phosphate pathway	3/178	30/8061	0.0277646916952764	n.a	3	0.1103897380655567	ALDOB, RGN, TALDO1
hsa05166	XX	e	Human T-cell leukemia virus 1 infection	10/178	219/8061	0.0301024968894922	n.a	10	0.1182598092087193	BAX, BCL2L1, CANX, CREBBP, FOS, IL6, JAK3, TNF, TP53, XIAP
hsa04915	XX	e	Estrogen signaling pathway	7/178	137/8061	0.0318120954220132	n.a	7	0.1235057822266395	CTSD, FOS, MMP2, MMP9, NOS3, PRKCD, SHC1
hsa04215	XX	e	Apoptosis - multiple species	3/178	32/8061	0.0328553220283508	n.a	3	0.1260727473180904	BAX, BCL2L1, XIAP
hsa05163	XX	e	Human cytomegalovirus infection	10/178	225/8061	0.0333083007561753	n.a	10	0.1263418304544582	BAX, CCL2, IFNA2, IL1B, IL6, PTGS2, TBK1, TNF, TP53, VEGFA
hsa05145	XX	e	Toxoplasmosis	6/178	112/8061	0.0373027789738684	n.a	6	0.1398854211520065	BCL2L1, IFNG, IRAK1, LDLR, TNF, XIAP
hsa04014	XX	e	Ras signaling pathway	10/178	232/8061	0.0378280071659228	n.a	10	0.1402611501657814	BCL2L1, FGF6, IGF1, LAT, PDGFA, PLA2G4A, SHC1, TBK1, TIAM1, VEGFA
hsa04610	XX	e	Complement and coagulation cascades	5/178	85/8061	0.0394874007688045	n.a	5	0.1441174181649501	CFH, CLU, FGA, PLAT, VWF
hsa05167	XX	e	Kaposi sarcoma-associated herpesvirus infection	9/178	193/8061	0.0397414698576074	n.a	9	0.1441174181649501	BAX, CREBBP, FOS, IFNA2, IL6, PTGS2, TBK1, TP53, VEGFA
hsa04370	XX	e	VEGF signaling pathway	4/178	59/8061	0.040863746346842	n.a	4	0.1450003902629877	NOS3, PLA2G4A, PTGS2, VEGFA
hsa04330	XX	e	Notch signaling pathway	4/178	59/8061	0.040863746346842	n.a	4	0.1450003902629877	CREBBP, NOTCH1, PSEN1, TLE3
hsa05226	XX	e	Gastric cancer	7/178	149/8061	0.0467094434246221	n.a	7	0.16397996095878	ABCB1, BAX, FGF6, RXRA, SHC1, TP53, WNT7A
hsa04071	XX	e	Sphingolipid signaling pathway	6/178	119/8061	0.0477978447681109	n.a	6	0.1660346186681748	BAX, CTSD, MAP3K5, NOS3, TNF, TP53
hsa05410	XX	e	Hypertrophic cardiomyopathy	5/178	90/8061	0.0485242944915247	n.a	5	0.1668022623146164	ACTB, AGT, IGF1, IL6, TNF
hsa05165	XX	e	Human papillomavirus infection	13/178	331/8061	0.0518622239270247	n.a	13	0.1748149636737158	BAX, CREBBP, IFNA2, NOTCH1, PSEN1, PTGS2, SPP1, TBK1, TNF, TP53, VEGFA, VWF, WNT7A
hsa04658	XX	e	Th1 and Th2 cell differentiation	5/178	92/8061	0.052454430983157	n.a	5	0.1748481032771902	FOS, IFNG, JAK3, LAT, NOTCH1
hsa05321	XX	e	Inflammatory bowel disease	4/178	65/8061	0.0549931003500425	n.a	4	0.1814772311551405	IFNG, IL1B, IL6, TNF
hsa00061	XX	e	Fatty acid biosynthesis	2/178	18/8061	0.0588601262669791	n.a	2	0.1923152640406248	ACSL1, FASN
hsa04666	XX	e	Fc gamma R-mediated phagocytosis	5/178	97/8061	0.0630711671827224	n.a	5	0.2040537761793961	ACTR3, GSN, LAT, PLA2G4A, PRKCD
hsa04926	XX	e	Relaxin signaling pathway	6/178	129/8061	0.0656843739862489	n.a	6	0.2104450817035159	FOS, MMP2, MMP9, NOS3, SHC1, VEGFA
hsa04640	XX	e	Hematopoietic cell lineage	5/178	99/8061	0.0676336670288247	n.a	5	0.2146068280722325	CD7, CSF3, IL1B, IL6, TNF
hsa04940	XX	e	Type I diabetes mellitus	3/178	43/8061	0.0686955688490877	n.a	3	0.2159003592399899	IFNG, IL1B, TNF
hsa04061	XX	e	Viral protein interaction with cytokine and cytokine receptor	5/178	100/8061	0.0699822309479561	n.a	5	0.2178692095549579	CCL2, CCR2, CXCL10, IL6, TNF
hsa00670	XX	e	One carbon pool by folate	2/178	20/8061	0.0710437117301664	n.a	2	0.2191067744949059	DHFR, MTHFR
hsa05146	XX	e	Amoebiasis	5/178	102/8061	0.0748132782634303	n.a	5	0.2285961280271483	ARG1, IFNG, IL1B, IL6, TNF
hsa04930	XX	e	Type II diabetes mellitus	3/178	46/8061	0.0806164354854673	n.a	3	0.2440681074330664	ADIPOQ, PRKCD, TNF
hsa00220	XX	e	Arginine biosynthesis	2/178	22/8061	0.0839602826613666	n.a	2	0.2518808479840999	ARG1, NOS3
hsa00620	XX	e	Pyruvate metabolism	3/178	47/8061	0.0847768131987533	n.a	3	0.252039174374672	DLAT, ME1, PC
hsa05220	XX	e	Chronic myeloid leukemia	4/178	76/8061	0.0868429775271186	n.a	4	0.2529323615037673	BAX, BCL2L1, SHC1, TP53
hsa05212	XX	e	Pancreatic cancer	4/178	76/8061	0.0868429775271186	n.a	4	0.2529323615037673	BAX, BCL2L1, TP53, VEGFA
hsa04510	XX	e	Focal adhesion	8/178	201/8061	0.0873766339740287	n.a	8	0.2529323615037673	ACTB, IGF1, PDGFA, SHC1, SPP1, VEGFA, VWF, XIAP
hsa04612	XX	e	Antigen processing and presentation	4/178	78/8061	0.0934231721673881	n.a	4	0.2680838853498964	CANX, HSPA5, IFNG, TNF
hsa04060	XX	e	Cytokine-cytokine receptor interaction	11/178	295/8061	0.1003399863689177	n.a	11	0.2854499612219211	CCL2, CCR2, CNTF, CSF3, CXCL10, IFNA2, IFNG, IL1B, IL6, TNF, TNFRSF21
hsa05206	XX	e	MicroRNAs in cancer	11/178	310/8061	0.1111998711433761	n.a	11	0.3136406621992661	ABCB1, CREBBP, HMOX1, MMP9, NOTCH1, PDGFA, PTGS2, SHC1, TP53, VEGFA, VIM
hsa04540	XX	e	Gap junction	4/178	88/8061	0.1296475524626145	n.a	4	0.3565307692721899	PDGFA, TUBA1A, TUBA4A, TUBB4B
hsa00020	XX	e	Citrate cycle (TCA cycle)	2/178	30/8061	0.1413162505072218	n.a	2	0.3854079559287869	DLAT, PC
hsa04015	XX	e	Rap1 signaling pathway	8/178	210/8061	0.1439059820254646	n.a	8	0.3892538858065846	ACTB, FGF6, IGF1, LAT, PDGFA, PFN1, TIAM1, VEGFA
hsa04730	XX	e	Long-term depression	3/178	60/8061	0.1462668158025627	n.a	3	0.3924231643483389	GRIA3, IGF1, PLA2G4A
hsa04810	XX	e	Regulation of actin cytoskeleton	8/178	218/8061	0.1529604792643836	n.a	8	0.4070722432036016	ACTB, ACTR3, FGF6, GSN, PDGFA, PFN1, TIAM1, TMSB4X
hsa04921	XX	e	Oxytocin signaling pathway	6/178	154/8061	0.156331377514849	n.a	6	0.4127148366392014	ACTB, CAMK1G, FOS, NOS3, PLA2G4A, PTGS2
hsa05217	XX	e	Basal cell carcinoma	3/178	63/8061	0.16210645463279	n.a	3	0.4214441209914253	BAX, TP53, WNT7A
hsa05414	XX	e	Dilated cardiomyopathy	4/178	96/8061	0.1621921314118515	n.a	4	0.4214441209914253	ACTB, AGT, IGF1, TNF
hsa00051	XX	e	Fructose and mannose metabolism	2/178	33/8061	0.1645330516379418	n.a	2	0.4241867737540687	ALDOB, SORD
hsa05231	XX	e	Choline metabolism in cancer	4/178	98/8061	0.1707586097535152	n.a	4	0.4334641632204618	FOS, PCYT1A, PDGFA, PLA2G4A
hsa04750	XX	e	Inflammatory mediator regulation of TRP channels	4/178	98/8061	0.1707586097535152	n.a	4	0.4334641632204618	IGF1, IL1B, PLA2G4A, PRKCD
hsa00010	XX	e	Glycolysis / Gluconeogenesis	3/178	67/8061	0.1839769451408864	n.a	3	0.4530775514663622	ALDOB, DLAT, ENO1
hsa04664	XX	e	Fc epsilon RI signaling pathway	3/178	68/8061	0.1895637629782726	n.a	3	0.4633780872802219	LAT, PLA2G4A, TNF
hsa04152	XX	e	AMPK signaling pathway	5/178	120/8061	0.1932387790615463	n.a	5	0.4655422111725097	ADIPOQ, FASN, IGF1, PPARG, PPARGC1A
hsa04919	XX	e	Thyroid hormone signaling pathway	5/178	121/8061	0.1949608518229747	n.a	5	0.4662107326201569	ACTB, CREBBP, NOTCH1, RXRA, TP53
hsa04611	XX	e	Platelet activation	5/178	124/8061	0.2005494591277355	n.a	5	0.4727237250868051	ACTB, FGA, NOS3, PLA2G4A, VWF
hsa04062	XX	e	Chemokine signaling pathway	7/178	192/8061	0.2033096338184944	n.a	7	0.4752344776575493	CCL2, CCR2, CXCL10, JAK3, PRKCD, SHC1, TIAM1
hsa05330	XX	e	Allograft rejection	2/178	38/8061	0.2044948358405212	n.a	2	0.4752344776575493	IFNG, TNF
hsa04520	XX	e	Adherens junction	3/178	71/8061	0.2065751846829748	n.a	3	0.4767119646530189	ACTB, CREBBP, SNAI1
hsa04650	XX	e	Natural killer cell mediated cytotoxicity	5/178	131/8061	0.2158958684399345	n.a	5	0.4913492178288165	IFNA2, IFNG, LAT, SHC1, TNF
hsa04068	XX	e	FoxO signaling pathway	5/178	131/8061	0.2158958684399345	n.a	5	0.4913492178288165	CAT, CREBBP, IGF1, IL6, SOD2
hsa05033	XX	e	Nicotine addiction	2/178	40/8061	0.2207760565949511	n.a	2	0.4990143744954374	GABRA1, GRIA3
hsa00380	XX	e	Tryptophan metabolism	2/178	42/8061	0.2371598027190335	n.a	2	0.5253971529550896	CAT, HADHA
hsa00860	XX	e	Porphyrin and chlorophyll metabolism	2/178	42/8061	0.2371598027190335	n.a	2	0.5253971529550896	CP, HMOX1
hsa05170	XX	e	Human immunodeficiency virus 1 infection	7/178	212/8061	0.2372247751221465	n.a	7	0.5253971529550896	BAX, BCL2L1, FOS, IFNA2, IRAK1, TBK1, TNF
hsa05100	XX	e	Bacterial invasion of epithelial cells	3/178	77/8061	0.2415364031453582	n.a	3	0.5313800869197881	ACTB, ACTR3, SHC1
hsa00071	XX	e	Fatty acid degradation	2/178	43/8061	0.2453775702286743	n.a	2	0.5362556170560433	ACSL1, HADHA
hsa04721	XX	e	Synaptic vesicle cycle	3/178	78/8061	0.2474609323870202	n.a	3	0.5372507084718201	SLC1A2, SLC6A1, UNC13A
hsa02010	XX	e	ABC transporters	2/178	45/8061	0.2618415842239684	n.a	2	0.5574691793155456	ABCB1, ABCC2
hsa04530	XX	e	Tight junction	6/178	169/8061	0.2785051890110797	n.a	6	0.5730977477231075	ACTB, ACTR3, MAP3K5, TIAM1, TUBA1A, TUBA4A
hsa04660	XX	e	T cell receptor signaling pathway	4/178	104/8061	0.2939398752386523	n.a	4	0.5987664125231806	FOS, IFNG, LAT, TNF
hsa04922	XX	e	Glucagon signaling pathway	4/178	107/8061	0.3013537092684627	n.a	4	0.6101026015864582	CREBBP, PPARA, PPARGC1A, PYGL
hsa04726	XX	e	Serotonergic synapse	4/178	113/8061	0.3181568497194398	n.a	4	0.6401936610208241	APP, CYP2C9, PLA2G4A, PTGS2
hsa04935	XX	e	"""Growth hormone synthesis, secretion and action"""	4/178	119/8061	0.337231418640353	n.a	4	0.674462837280706	CREBBP, FOS, IGF1, SHC1
hsa00240	XX	e	Pyrimidine metabolism	2/178	57/8061	0.359789285195105	n.a	2	0.7152437597252087	NME2, PNP
hsa05213	XX	e	Endometrial cancer	2/178	58/8061	0.3677814311826319	n.a	2	0.726753726289033	BAX, TP53
hsa04978	XX	e	Mineral absorption	2/178	59/8061	0.3757349454272951	n.a	2	0.7380507856607583	HMOX1, TRPM7
hsa04145	XX	e	Phagosome	5/178	152/8061	0.3914361006831044	n.a	5	0.7598465483848498	ACTB, CANX, TUBA1A, TUBA4A, TUBB4B
hsa04310	XX	e	Wnt signaling pathway	5/178	166/8061	0.4187388742675541	n.a	5	0.78069959609205	CREBBP, PSEN1, TLE3, TP53, WNT7A
hsa05210	XX	e	Colorectal cancer	3/178	86/8061	0.4405733244914193	n.a	3	0.8083590784764001	BAX, FOS, TP53
hsa05235	XX	e	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/178	89/8061	0.4492767913578099	n.a	3	0.8191234317573332	FOS, IFNG, LAT
hsa04912	XX	e	GnRH signaling pathway	3/178	93/8061	0.4618752408139958	n.a	3	0.8302101088218062	MMP2, PLA2G4A, PRKCD
hsa04350	XX	e	TGF-beta signaling pathway	3/178	94/8061	0.4651821925341383	n.a	3	0.8302101088218062	CREBBP, IFNG, TNF
hsa04925	XX	e	Aldosterone synthesis and secretion	3/178	98/8061	0.4789546341737459	n.a	3	0.8452140603066105	AGT, CAMK1G, LDLR
hsa03015	XX	e	mRNA surveillance pathway	3/178	98/8061	0.4789546341737459	n.a	3	0.8452140603066105	FUS, GLE1, TARDBP
hsa04928	XX	e	"""Parathyroid hormone synthesis, secretion and action"""	3/178	106/8061	0.5085813076192423	n.a	3	0.8741241224705727	FOS, JUND, RXRA
hsa04910	XX	e	Insulin signaling pathway	4/178	137/8061	0.54805264245458	n.a	4	0.8997879204478177	FASN, PPARGC1A, PYGL, SHC1
hsa04371	XX	e	Apelin signaling pathway	4/178	137/8061	0.54805264245458	n.a	4	0.8997879204478177	NOS3, PLAT, PPARGC1A, SPP1
hsa05017	XX	e	Spinocerebellar ataxia	4/178	143/8061	0.559721975151257	n.a	4	0.9098928660094326	ATXN2, ERN1, GRIA3, MAP3K5
hsa04072	XX	e	Phospholipase D signaling pathway	4/178	148/8061	0.5705747759428987	n.a	4	0.9175767159945136	AGT, PDGFA, PLA2G4A, SHC1
hsa04150	XX	e	mTOR signaling pathway	4/178	154/8061	0.5847134904460916	n.a	4	0.9274623609216588	IGF1, SESN2, TNF, WNT7A
hsa04934	XX	e	Cushing syndrome	4/178	155/8061	0.5871713573820128	n.a	4	0.9274623609216588	AGT, AHR, LDLR, WNT7A
hsa04927	XX	e	Cortisol synthesis and secretion	2/178	65/8061	0.6554062666146496	n.a	2	0.9618050167666196	AGT, LDLR
hsa04020	XX	e	Calcium signaling pathway	6/178	240/8061	0.6557761477954224	n.a	6	0.9618050167666196	CAMK1G, ERBB4, FGF6, NOS3, PDGFA, VEGFA
hsa05031	XX	e	Amphetamine addiction	2/178	69/8061	0.6655359526420275	n.a	2	0.9629132340497386	FOS, GRIA3
hsa05211	XX	e	Renal cell carcinoma	2/178	69/8061	0.6655359526420275	n.a	2	0.9629132340497386	CREBBP, VEGFA
hsa04917	XX	e	Prolactin signaling pathway	2/178	70/8061	0.6682034260526974	n.a	2	0.9629132340497386	FOS, SHC1
hsa04012	XX	e	ErbB signaling pathway	2/178	85/8061	0.7121624128112182	n.a	2	1.0	ERBB4, SHC1
hsa04512	XX	e	ECM-receptor interaction	2/178	88/8061	0.7214078538216219	n.a	2	1.0	SPP1, VWF
hsa04727	XX	e	GABAergic synapse	2/178	89/8061	0.7244970396202088	n.a	2	1.0	GABRA1, SLC6A1
hsa04670	XX	e	Leukocyte transendothelial migration	3/178	114/8061	0.7411579786761209	n.a	3	1.0	ACTB, MMP2, MMP9
hsa04724	XX	e	Glutamatergic synapse	3/178	114/8061	0.7411579786761209	n.a	3	1.0	GRIA3, PLA2G4A, SLC1A2
hsa04110	XX	e	Cell cycle	3/178	124/8061	0.7550601191678077	n.a	3	1.0	CREBBP, PRKDC, TP53
hsa04142	XX	e	Lysosome	3/178	128/8061	0.7613375133058322	n.a	3	1.0	CD68, CTSD, CTSE
hsa04728	XX	e	Dopaminergic synapse	3/178	132/8061	0.7679222040670481	n.a	3	1.0	FOS, GRIA3, KIF5A
hsa04270	XX	e	Vascular smooth muscle contraction	3/178	133/8061	0.7696091098519443	n.a	3	1.0	AGT, PLA2G4A, PRKCD
hsa04218	XX	e	Cellular senescence	4/178	156/8061	0.7788605507157771	n.a	4	1.0	IL6, SQSTM1, TP53, TRPM7
hsa05203	XX	e	Viral carcinogenesis	5/178	203/8061	0.8059777140355975	n.a	5	1.0	BAX, CREBBP, GSN, JAK3, TP53
hsa04024	XX	e	cAMP signaling pathway	5/178	216/8061	0.813814723413327	n.a	5	1.0	CREBBP, FOS, GRIA3, PPARA, TIAM1
hsa05168	XX	e	Herpes simplex virus 1 infection	11/178	498/8061	1.0	n.a	11	1.0	BAX, BCL2L1, CCL2, IFNA2, IFNG, IL1B, IL6, IRAK1, TBK1, TNF, TP53
hsa04080	XX	p	Neuroactive ligand-receptor interaction	4/178	341/8061	0.2549441464622656	n.a	4	0.5463088852762834	AGT, GABRA1, GRIA3, PENK
hsa04390	XX	p	Hippo signaling pathway	2/178	157/8061	0.5873928285837171	n.a	2	0.9274623609216588	ACTB, WNT7A
hsa04144	XX	p	Endocytosis	4/178	252/8061	0.6632564057971067	n.a	4	0.9629132340497386	ACTR3, CHMP2B, KIF5A, LDLR
hsa05322	XX	p	Systemic lupus erythematosus	2/178	135/8061	0.7715124105749298	n.a	2	1.0	IFNG, TNF
hsa04120	XX	p	Ubiquitin mediated proteolysis	2/178	140/8061	0.771913122967334	n.a	2	1.0	PRKN, XIAP
hsa03040	XX	p	Spliceosome	2/178	151/8061	0.7758509332329435	n.a	2	1.0	FUS, HNRNPA1
hsa03013	XX	p	RNA transport	3/178	186/8061	0.8005381196113823	n.a	3	1.0	FUS, GLE1, TARDBP
hsa04550	XX	p	Signaling pathways regulating pluripotency of stem cells	3/178	143/8061	1.0	n.a	3	1.0	IGF1, JAK3, WNT7A
hsa04714	XX	p	Thermogenesis	5/178	232/8061	1.0	n.a	5	1.0	ACSL1, ACTB, MAP3K5, PPARG, PPARGC1A
hsa00564	XX	p	Glycerophospholipid metabolism	2/178	98/8061	1.0	n.a	2	1.0	PCYT1A, PLA2G4A
hsa00230	XX	p	Purine metabolism	2/178	129/8061	1.0	n.a	2	1.0	NME2, PNP
hsa05150	XX	p	Staphylococcus aureus infection	2/178	95/8061	1.0	n.a	2	1.0	CFH, SELPLG
hsa04723	XX	p	Retrograde endocannabinoid signaling	3/178	148/8061	1.0	n.a	3	1.0	GABRA1, GRIA3, PTGS2
hsa04916	XX	p	Melanogenesis	2/178	101/8061	1.0	n.a	2	1.0	CREBBP, WNT7A
hsa04713	XX	p	Circadian entrainment	2/178	97/8061	1.0	n.a	2	1.0	FOS, GRIA3